# 208. 7-OH, sold at gas stations, slows respiration beyond sleep…not yet controlled!
# 208
Alert for 7-OH, not currently on the Schedule prepared by DEA and Congress. Available at gas stations.
https://www.fda.gov/news-events/public-health-focus/hiding-plain-sight-7-oh-products
7-OH produces severe respiratory depression. It responds to Narcan, however, a user can lapse back into sleep or worse.
Narcan?
Yes, an overdose from 7-OH (7-hydroxymitragynine) can be reversed with Narcan (naloxone)because 7-OH binds to the body's opioid receptors and can cause dangerous breathing slowdowns. However, professional medical help is still required immediately. [1, 2]
What to Do in an Emergency
- Call 911 right away if you think someone has overdosed.
- Give Narcan (naloxone) right away if you have it.
Important Safety Facts
- Repeated Doses: Because concentrated 7-OH is very strong, a person may need more than one dose of Narcan.
- Returning Risks: Narcan wears off faster than some strong opioids. Breathing trouble and severe sleepiness can come back after the spray wears off.
Further Exploration
- Review clinical data on 7-Hydroxymitragynin (7-OH) Assessment from the FDA.
- Read safety details from the Missouri Department of Health.
- Learn about clinical risks in the report by ISSUP.

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